Written Works
In this section, you’ll find highlights of my written work from college, showcasing a few of the assignments and projects I've completed while at LSU. These include a technical final report from a group project, detailed research papers on bioengineering-related topics, and an involved independent study emphasizing data analysis. Each project reflects my growth as a writer and a researcher as well as my commitment to thorough and well-explained communication within the biological engineering field and beyond.
Updating Survival Probabilities after Hematopoietic Stem Cell Transplantation for Patients with Cerebral Adrenoleukodystrophy
BE 4910: Data Analysis and Modeling in Biological Engineering
After donating bone marrow through NMDP, I wanted to quantify my recipient's outlook based on the limited information I had about my donation. This incredibly rewarding experience also served as an ideal final project for my data analysis class. As such, I estimated adrenoleukodystrophy patient survival probabilities after hematopoietic stem cell transplantation using Bayesian updating with MATLAB-based data analysis. This analysis assessed post-transplant survival at key timepoints (100 days, 1 year, 2 years) using recipient-donor factors like HLA match status and donation type. I successfully utilized transplantation variable information from multiple studies to generate probability distributions and estimate my recipient's survival probability while accounting for the facts that I donated bone marrow and am unrelated to my recipient.
Lactic Acid Production
BE 3340: Process Design
with Claire Bougere, Carlie Dutile, Raymond Martin, and Anna Claire Ricks-boyd
My group and I completed a detailed technical report on lactic acid production, examining its commercial significance, various applications, and common production methods. I played a key role in conducting a literature review of over 40 sources and evaluating the advantages and disadvantages of different production methods with an emphasis on upstream production. Our group considered these methods in proposing an optimized production approach using corn grain as the feedstock. We then modeled our chosen process in SuperPro Designer, creating a comprehensive simulation to analyze production efficiency.
DNA Topoisomerase Case Study
BIOL 2083: Biochemistry
This case study provides a comprehensive analysis of the human DNA Topoisomerase I enzyme including structural descriptions, structural comparisons between different sources, functional details, and its physiological significance. In this report, I emphasize the fundamental dependence of enzymatic function on structure and explore how the structure of DNA Topoisomerase has been leveraged as a target for potential cancer therapeutics.
Base Editors and Their Potential to Treat Genetic Diseases
BE 2352: Quantitative Biology in Engineering
This report for an independent study of base editors explores the mechanisms of base editing, different types of base editors, and this strategy's advantages over traditional gene-editing methods. Potential in vivo applications are also discussed while acknowledging the limitations of this relatively new technique that must be addressed before base editors are clinically applied.
